The M7250 model delivers the finest and most uniform distribution of submicron particle size at the highest shear rates available. The M7250 delivers repeatable results from lab and pilot scale to production volumes.

Ultra-High Shear Manufacturing Processing

Once the suitable pilot batches are achieved, scale up seamlessly to full production with one of the M700 series models.

The M700 series processors have proven to be cost-effective in a broad range of industries. Utilizing the Microfluidizer® technology, these processors deliver the finest and most uniform distribution of submicron particle size at the highest shear rates available. Emulsions and suspensions are more stable, creating superior final products.

The M700 series machines have the same high-pressure, multi-slotted fixed-geometry Interaction ChambersTM that all the Microfluidics equipment possess. It means that identical high shear rates are imparted to product formulations as are achieved on lab scale and pilot scale machines through scalable Interaction ChambersTM.

The M7125 and M7250 models generate up to 30,000 psi operating pressure for premium results at an affordable cost. Flow rates of 300 to 900 L/hr are achievable with the right model.

A broad range of throughput in continuous or batch mode is possible due to the fact that the machine can process at a wide range of pressures and flows.

Standard Features

Proven to be highly reliable at operating pressures up to 30,000 psi in pilot and production environments.
Generates the highest shear rates of any fluid processor on the market today, which results most often in achieving desired product quality in a single pass.
Wear-resistant Interaction Chamber™ with fixed-geometry design ensures that the entire product stream encounters equal energy-per-unit fluid volume.
Highly durable intensifier pumping system is efficient at ultra-high pressures.
High-pressure plunger seals and check valves
Model M7250 unit comes standard with two synchronized intensifier pumps for increased flow rates.
Open isolator to prevent process fluid and hydraulic fluid contact.
Simple, efficient electric/hydraulic drive system
Coned and threaded tubing and fittings
In-line cleaning with no disassembly required
All stainless-steel construction
Validatable for cGMP and cGAMP applications

Standard Features of the M710 Processor Model

Dual synchronous intensifier pump provides reproducible, reliable results.
Constant pressure feature is available with M710 machines operating at process pressures of 1379 bar (20,000 psi) and above.
Wear-resistant Interaction Chamber™ technology maximizes energy-per-unit volume of product.
Highest shear rates of all available competitive processors.
Easy in-line cleaning and simple maintenance.

Pharma and Biotech

Options are available for production scale processing to meet the needs of pharma and biotech customers. A range of options are available to suit specific requirements.

The M700 Series can be designed to achieve cGMP standards. Each machine comes standard with a feed pump and heat exchanger, which makes it easy to use simply by attaching the feed vessel and collection vessel then it's ready to run.

Basic Biopharma:

cGMP as specified by the American Society for Mechanical Engineers – Material Certificates for all product contact parts included in an electronic Turnover Package (TOP)
Surface Finish – Electropolished and passivated - surface finish of < 20 Ra
USP Class VI elastomers
Drainability – A sanitary heat exchanger, a sanitary flush pressure transducer and pitched piping are included to ensure all equipment can be drained effectively
CIP - clean in place

Enhanced Biopharma:

Includes all of the features of the Basic Biopharma machine plus:
21 CFR Part 11 Data Acquisition
Industrial Personal Computer (IPC)
Other options include - automation, conductivity sensors & mass flow meter

Aseptic Biopharma:

All of the features of the Enhanced Biopharma machine plus:
Steam in Place (SIP) for processing in a sterile environment
Equipment is fully automated
Also recipes for Steam, Prime, Run & Drain

Recommended Uses

Models M7125 and M7250 are recommended for:

Immiscible Liquid Emulsions
Solid-in-Liquid Suspensions
Submicron Particle Size Reduction
Deagglomeration and Dispersion

The M710 Production Model is recommended for:

Stable Solid-in-Liquid Dispersions
Stable Microemulsions
Submicron Particles (Nanoparticles)
Deagglomeration

Specifications

Specifications for the M7125 model:

Operating pressure of up to 30,000 psi/2068 bar
Flow rate up to 7.56 lpm (2.0 gpm)
Power - 18.6 kw (25 HP)

Specifications for the M7250 model:

Operating pressure of up to 30,000 psi/2068 bar
Flow rate up to 15.12 lpm (4.0 gpm)
Power - 37.3 kw (50 HP) /

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