Automated Parallel Peptide Synthesizer MultiPep 2

The MultiPep 2 is the state of the art automated parallel peptide synthesizer. It features unmatched flexibility for screening hundreds of peptides in parallel using plates, columns, or cellulose membranes formats.

Flexible Formats

• Plates = up to 384 (4 x 96) peptides at 1-10 μmol
• Columns = 48 mini-columns (0.25, 0.50 mL) - 1-15μmol

       48 columns (2,5,10,20 mL) - 10-500μmol

       72 columns (2,5,10 mL) - 10-300μmol

• SPOT Synthesis = up to 2400 peptides on four cellulose membranes
• CelluSpots™ = up to 768 peptides on a dissolvable cellulose support for spotting on many identical slides

Features

• Heating option for elevated temperature synthesis in plates and columns
• Fast synthesis with 8 position parallel washing arm
• Vortex mixing
• Pre-activation or in-situ activation

Peptide Libraries

Peptide synthesis with 96 well plates and columns

Easily synthesize large libraries of peptides using a 96 well plate with the MultiPep 2. Use up to 4 x 96 well plates at one time for the parallel synthesis of 384 peptides. Mini-columns (up 0.5mL) can be used to synthesize up to 72 peptides in parallel. Alternatively, 48 larger columns (2, 5, or 10 mL size) can be used in parallel.

Integrated Heating Module

Parallel peptide synthesis at elevated temperature.

Apply elevated temperature synthesis conditions to either 96 well plates or columns run on the MultiPep 2. This is made easy with optional heating block accessories with adjustable temperature control. Elevated temperature is helpful for improving the purity of difficult and longer sequences.

SPOT Synthesis

Peptide microarrays

SPOT synthesis allows for the synthesis of thousands of immobilized peptides on cellulose membranes. This is useful for on-support binding studies as well as solution and cell based assays. With the MultiPep 2 the SPOT synthesis option allows for the synthesis of up to 2400 peptides in a batch for high-throughput screening applications.  

CelluSpots

Easily make many copies of a peptide array on glass slides.

Easily make many copies of a peptide array on glass slides. CelluSpots technology combines the advantages of traditional SPOT synthesis with a unique dissolvable cellulose support for making many identical copies of a peptide array. Based on the use of the unique Slide Spotting robot after SPOT synthesis on the dissolvable cellulose support.

Peptide Nucleic Acids

Optimized PNA Synthesis

The MultiPep 2 is a powerful tool for small scale synthesis requiring expensive monomers such as PNA. Perform PNA synthesis as low as 1μmol with the small fluid delivery capabilities of the MultiPep 2. Up to 48 smaller columns in parallel (250μL, 500μL sizes) can be used.

Software

Intuitive and flexible

The MultiPep 2 allows easy programming with useful tools including:

• Importing and exporting sequences
• Preconfigured synthesis protocols
• Prediction of difficult sequences
• Calculation of reagent consumption
• Real-time display of operations
• Detailed documentation of each run