MM 500 Vario Vibratory Mill — Versatile Laboratory Grinding | Makrolab
The new Mixer Mill MM 500 vario is a versatile bench-top unit which provides ultimate performance with maximum flexibility for your sample preparation process.
It is used for dry, wet and cryogenic grinding of small sample amounts with high throughput. The MM 500 vario can be equipped with screw-top grinding jars from 1.5 ml to 50 ml. Available materials include hardened steel, stainless steel, tungsten carbide, agate, zirconium oxide, PTFE.
For biological applications such as homogenization of plant materials, tissues or for cell disruption via bead beating, the MM 500 vario can be equipped with different adapters for single-use vials from 0.2 - 5 ml.
THE STRONG MIXER MILL FOR HIGH THROUGHPUT APPLICATIONS
Max. speed 35 Hz
Horizontal oscillation causes strong impact effects for effective sample processing
Up to 8 mm feed size and 5 µm final fineness
6 grinding stations for jars of min. 2 ml and max. 50 ml, adapter holds up to 50 x 2 ml single use vials
Steel jars can be precooled manually in liquid nitrogen
Bench-top model, touch screen, storable SOPs and cycle programs, 7 different jar materials
SOLUTIONS FOR BIOLOGICAL APPLICATIONS AND CELL DISRUPTION
Mixer mills are widely used for homogenizing biological samples such as tissue, liver, muscle, plants, corn or sputum. For cell disruption via bead beating mixer mills are also the perfect solution. The MM 500 vario accommodates adapters for different single-use vials:
0.2 ml / 1.5 ml / 2 ml / 5 ml
Depending on the tube and the type of adapter, 5-10 tubes can be inserted per adapter, resulting in the following maximum vial capacity per batch:
50 x 1.5 or 2 ml (or 60 x 0.2 ml)
20 x 5 ml
Typical grinding / homogenizing processes of biological materials take less than 2 min. Cell disruption with a good reproducibility and efficiency takes 20 sec to 5 min, depending on the cell type. Cryogenic grinding in single-use vials can also be a suitable way to pulverize tough or temperature-sensitive samples.
MAXIMIZE YOUR THROUGHPUT
Maximum frequency of 35 Hz reduces grinding time to 50% compared to mixer mills with only 30 Hz
Six grinding stations instead of two, as in classic mixer mills, ensure high throughput
In combination, the throughput of the MM 500 vario is 6 times higher compared to a classic mixer mill
Grinding of basalt in the MM 500 vario results in better fineness compared to classic Mixer Mills thanks to the increased frequency of 35 Hz instead of 30 Hz (50 ml jar + 12 x 12 mm grinding balls).
TYPICAL SAMPLE MATERIALS
RETSCH mixer mills are true allrounders. They homogenize, for example, waste, soil, chemical products, coated tablets, drugs, ores, grain, tissue, glass, hair, ceramics, bones, plastics, alloys, minerals, oil seeds, plants, sewage sludge, pills, textiles, wool etc.
*depending on feed material and instrument configuration/settings
FUNCTIONAL PRINCIPLE
The grinding jars of the mixer mill MM 500 vario perform radial oscillations in a horizontal position. The inertia of the grinding balls causes them to impact with high energy on the sample material at the rounded ends of the grinding jars and pulverize it. Also, the movement of the grinding jars combined with the movement of the balls result in the intensive mixing of the sample. The degree of mixing can be increased even further by using several smaller balls.
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Grinding of basalt in the MM 500 vario results in better fineness compared to classic Mixer Mills thanks to the increased frequency of 35 Hz instead of 30 Hz (50 ml jar + 12 x 12 mm grinding balls).
